トルエン MSDS

1. IDENTIFICATION
Synonyms: Methylbenzene; Toluol; Phenylmethane
CAS No.: 108-88-3
Molecular Weight: 92.14
Chemical Formula: C6H5-CH3

2. COMPOSITION
Ingredient CAS No Percent Hazardous
Toluene 108-88-3 100% Yes

3. HAZARDS IDENTIFICATION
Emergency Overview
POISON! DANGER! HARMFUL OR FATAL IF SWALLOWED. HARMFUL IF INHALED OR ABSORBED
THROUGH SKIN. VAPOR HARMFUL. FLAMMABLE LIQUID AND VAPOR. MAY AFFECT LIVER, KIDNEYS,
BLOOD SYSTEM, OR CENTRAL NERVOUS SYSTEM. CAUSES IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT.
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Health Rating: 2 - Moderate
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 0 - None
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
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Potential Health Effects
Inhalation: Inhalation may cause irritation of the upper respiratory tract. Symptoms of overexposure may
include fatigue, confusion, headache, dizziness and drowsiness. Peculiar skin sensations (e.g., pins and
needles) or numbness may be produced. Very high concentrations may cause unconsciousness and death.
Ingestion: Swallowing may cause abdominal spasms and other symptoms that parallel over-exposure from
inhalation. Aspiration of material into the lungs can cause chemical pneumonitis, which may be fatal.
Skin Contact: Causes irritation. May be absorbed through skin.
Eye Contact: Causes severe eye irritation with redness and pain.
Chronic Exposure: Reports of chronic poisoning describe anemia, decreased blood cell count and bone
marrow hypoplasia. Liver and kidney damage may occur. Repeated or prolonged contact has a defatting
action, causing drying, redness, dermatitis. Exposure to toluene may affect the developing fetus.
Aggravation of Pre-existing Conditions: Persons with pre-existing skin disorders or impaired liver or kidney
function may be more susceptible to the effects of this substance. Alcoholic beverage consumption can
enhance the toxic effects of this substance.

4. FIRST AID MEASURES
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. CALL A PHYSICIAN IMMEDIATELY.
Ingestion: Aspiration hazard. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never
give anything by mouth to an unconscious person. Get medical attention immediately. If vomiting occurs,
keep head below hips to prevent aspiration into lungs.
Skin Contact: In case of contact, immediately flush skin with plenty of soap and water for at least 15 minutes
while removing contaminated clothing and shoes. Wash clothing before reuse. Call a physician
immediately.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper
eyelids occasionally. Get medical attention immediately.

5. FIRE FIGHTING MEASURES
Fire: Flash point: 7 ℃ (45°F) CC; Autoignition temperature: 422 ℃ (792°F)
Flammable limits in air % by volume: lel: 3.3; uel: 19; Flammable liquid and vapor! Dangerous fire hazard
when exposed to heat or flame. Vapors can flow along surfaces to distant ignition source and flash back.
Explosion: Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Contact
with strong oxidizers may cause fire or explosion. Sensitive to static discharge.
Fire Extinguishing Media: Dry chemical, foam or carbon dioxide. Water may be used to flush spills away
from exposures and to dilute spills to non-flammable mixtures.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained
breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Water spray may be used to keep fire exposed containers cool.

6. ACCIDENTAL RELEASE MEASURES
Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective
equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel
from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect
liquid in an appropriate container or absorb with an inert material (e.g., vermiculite, dry sand, earth), and
place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to
sewer! If a leak or spill has not ignited, use water spray to disperse the vapors, to protect personnel
attempting to stop leak, and to flush spills away from exposures. US Regulations (CERCLA) require
reporting spills and releases to soil, water and air in excess of reportable quantities.

7. HANDLING AND STORAGE
Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the
fire hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles.
Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas
should be No Smoking areas. Use non-sparking type tools and equipment, including explosion proof
ventilation. Containers of this material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the product.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Airborne Exposure Limits:
OSHA Permissible Exposure Limit (PEL): 200 ppm (TWA); 300 ppm (acceptable ceiling conc.); 500 ppm
(maximum conc.). ACGIH Threshold Limit Value (TLV): 50 ppm (TWA) skin, A4 - Not Classifiable as a
Human Carcinogen.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures
below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control
the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please
refer to the ACGIH document,
Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): If the exposure limit is exceeded and engineering controls are not
feasible, a half-face organic vapor respirator may be worn for up to ten times the exposure limit, or the
maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever
is lowest. A full-face piece organic vapor respirator may be worn up to 50 times the exposure limit, or the
maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever
is lowest. For emergencies or instances where the exposure levels are not known, use a full-face piece
positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in
oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls,
as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain
eye wash fountain and quick-drench facilities in work area.

9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Clear, colorless liquid.
Odor: Aromatic benzene-like.
Solubility: 0.05 gm/100 gm water @ 20 ℃ (68°F).
Specific Gravity: 0.86 @ 20 ℃ / 4 ℃
pH: No information found.
% Volatiles by volume @ 21 ℃ (70°F): 100
Boiling Point: 111 ℃ (232°F)
Melting Point: .95 ℃ (.139°F)
Vapor Density (Air=1): 3.14
Vapor Pressure (mm Hg): 22 @ 20 ℃ (68°F)
Evaporation Rate (BuAc=1): 2.24

10. STABILITY AND REACTIVITY
Stability: Stable under ordinary conditions of use and storage. Containers may burst when heated.
Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to
decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Heat, flame, strong oxidizers, nitric and sulfuric acids, chlorine, nitrogen tetraoxide; will
attack some forms of plastics, rubber, coatings.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles.

11. TOXICOLOGICAL INFORMATION
Toxicological Data: Oral rat LD50: 636 mg/kg; skin rabbit LD50: 14100 uL/kg; inhalation rat LC50: 49
gm/m3/4H; Irritation
data: skin rabbit, 500 mg, Moderate; eye rabbit, 2 mg/24H, Severe. Investigated as a tumorigen, mutagen,
reproductive effector.
Reproductive Toxicity: Has shown some evidence of reproductive effects in laboratory animals.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
Toluene (108-88-3) No No 3

12. ECOLOGICAL INFORMATION
Environmental Fate: When released into the soil, this material may evaporate to a moderate extent. When
released into the soil, this material is expected to leach into groundwater. When released into the soil, this
material may biodegrade to a moderate extent. When released into water, this material may evaporate to a
moderate extent. When released into water, this material may biodegrade to a moderate extent. When
released into the air, this material may be moderately degraded by reaction with photochemically produced
hydroxyl radicals. When released into the air, this material is expected to have a half-life of less than 1 day.
This material is not expected to significantly bioaccumulate. This material has a log octanol-water partition
coefficient of less than 3.0. Bioconcentration factor = 13.2 (eels).
Environmental Toxicity: This material is expected to be toxic to aquatic life. The LC50/96-hour values for fish
are between 10 and 100 mg/l.

13. DISPOSAL CONSIDERATIONS
Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a
RCRA approved incinerator or disposed in a RCRA approved waste facility. Processing, use or
contamination of this product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations. Dispose of container and unused contents in
accordance with federal, state and local requirements.

14. TRANSPORT INFORMATION
Domestic (Land, D.O.T.)
Proper Shipping Name: TOLUENE
Hazard Class: 3
UN/NA: UN1294
Packing Group: II
Information reported for product/size: 390LB
International (Water, I.M.O.)
Proper Shipping Name: TOLUENE
Hazard Class: 3
UN/NA: UN1294
Packing Group: II
Information reported for product/size: 390LB

15. REGULATORY INFORMATION
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
Toluene (108-88-3) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
Toluene (108-88-3) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
Toluene (108-88-3) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCAIngredient
CERCLA 261.33 8(d)
Toluene (108-88-3) 1000 U220 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: Yes
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
WARNING: THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO
CAUSE BIRTH DEFECTS OR OTHER REPRODUCTIVE HARM.
Australian Hazchem Code: 3[Y]E
Poison Schedule: S6

16. OTHER INFORMATION
NFPA Ratings: Health: 2 Flammability: 3 Reactivity: 0
Label Hazard Warning: POISON! DANGER! HARMFUL OR FATAL IF SWALLOWED. HARMFUL IF INHALED
OR ABSORBED THROUGH SKIN. VAPOR HARMFUL. FLAMMABLE LIQUID AND VAPOR. MAY AFFECT
LIVER, KIDNEYS, BLOOD SYSTEM, OR CENTRAL NERVOUS SYSTEM. CAUSES IRRITATION TO SKIN,
EYES AND RESPIRATORY TRACT.
Label Precautions: Keep away from heat, sparks and flame. Keep container closed. Use only with adequate
ventilation.
Wash thoroughly after handling. Avoid breathing vapor. Avoid contact with eyes, skin and clothing.
Label First Aid: Aspiration hazard. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water.
Never give anything by mouth to an unconscious person. If vomiting occurs, keep head below hips to prevent
aspiration into lungs. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact, immediately flush eyes or skin with plenty of water for at least 15
minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. In all cases call a
physician immediately.
Product Use: Laboratory Reagent.